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It can also contribute to age-related macular degeneration (AMD), a condition that causes loss of central vision

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Sci Rep 8:1145 Gonzalez Suarez I, Martin F, Marescotti D, Guedj E, Acali S, Johne S, Dulize R, Baumer K, Peric D, Goedertier D, Frentzel S, Ivanov N, Mathis C, Hoeng J, Peitsch MC (2016) In vitro systems toxicology assessment of a candidate modified risk tobacco product shows reduced toxicity compared to a conventional cigarette

Studies in twins report that 60% of the individual susceptibility to develop COPD depends on genetic factors 21